Berberine Benefits: What 46 Trials Show, Plus the Side Effects
Berberine benefits in trials are modest. A review of 46 studies found small drops in blood sugar and blood fats, mostly as an add-on to standard care, and weight fell about 2 kg or less. Side effects are mainly nausea, diarrhea and constipation. Berberine can raise cyclosporine levels, affect diabetes medicines, and should not be used in pregnancy, breastfeeding or infancy.